HORIZON-MISS-2027-02-CANCER-01: Leveraging functional genomics to reveal novel targets for cancer treatment (RIA)

HORIZON-MISS-2027-02-CANCER-02: Clinical research by Comprehensive Cancer Infrastructures for the benefit of patients with common cancers (IA)

HORIZON-MISS-2027-02-CANCER-03: Phase 1 including first-in-human clinical trials to test biomarker-guided medicines or multimodal treatment interventions for patients with rare or very rare cancers or cancer subtypes (RIA)

HORIZON-MISS-2027-02-CANCER-04: Improving equitable health outcomes and added value for and with cancer patients through health-economics research, health systems research and outcomes research (RIA)

HORIZON-MISS-2027-02-CANCER-05: Precommercial procurement of affordable solutions for healthcare systems in the areas of cancer technologies, cancer medical devices, or cancer medicines (PCP)

HORIZON-MISS-2027-02-CANCER-06: Support a Young Cancer Survivor Quality of Life (QoL) research programme by cancer charities and funding agencies (CSA)

The call opens on 10th February 2027

At the moment, the topics are not available on Funding and Tenders Portal. We'll include the links as soon they become available. Until then, the topic texts are available in Work Programme of Missions of Horizon Europe (topics of cancer mission call 2027 start from page 87)

HORIZON-MISS-2027-06-SOIL-CANCER: Living labs to monitor and mitigate carcinogenic substances in and originating from soils: Evaluating their effects on human cancer risks (RIA)

The call opens on 4th February 2027

HORIZON-HLTH-2027-01-CARE-02: Personalised approaches to reduce risks from Adverse Drug Reactions due to administration of multiple medications (RIA)

The call opens on 10th February 2027 

HORIZON-HLTH-2026-03-DISEASE-13: European Partnership for Pandemic Preparedness (Phase 2) (Programme Cofund Actions)

HORIZON-HLTH-2027-02-DISEASE-01-two-stage: Innovative healthcare interventions for non-communicable diseases (RIA)

HORIZON-HLTH-2027-01-DISEASE-05: Development of novel small molecule antiviral therapeutics for pathogens with epidemic potential (RIA)

HORIZON-HLTH-2027-01-DISEASE-06: Development of monoclonal antibodies to prevent and treat infections from Flaviviruses (RIA)

HORIZON-HLTH-2027-01-DISEASE-07: Development of monoclonal antibodies to prevent and treat infections from Filo-, Nairo-, Phenui-, Picorna- and Toga viruses (RIA)

HORIZON-HLTH-2027-01-DISEASE-08: Development of innovative antimicrobials against pathogens resistant to antimicrobials (RIA)

HORIZON-HLTH-2027-01-DISEASE-10: Prevention and management of chronic non-communicable diseases in children and young people (GACD) (RIA)

HORIZON-HLTH-2027-02-DISEASE-14-two-stage: Clinical trials for advancing innovative interventions for neurodegenerative diseases (RIA)

The call opens on 10th February 2027. 

HORIZON-HLTH-2027-01-ENVHLTH-02: Integrating climate-related exposures into the human exposome and characterising its changes in response to climate change (RIA)

HORIZON-HLTH-2027-01-ENVHLTH-MISSCLIMA-03: Tools and technologies to support health adaptation to climate change (PCP)

The call opens on 10th February 2027. 

HORIZON-HLTH-2027-02-TOOL-01-two-stage: Development of predictive biomarkers of disease progression and treatment response by using AI methodologies for chronic non-communicable diseases (RIA)

HORIZON-HLTH-2027-03-TOOL-02: Advancing bio-printing of living cells for regenerative medicine (RIA)

HORIZON-HLTH-2027-03-TOOL-04: Virtual Human Twins (VHTs) for integrated clinical decision support in prevention and diagnosis (RIA)

HORIZON-HLTH-2027-03-TOOL-08: Towards Artificial General Intelligence (AGI) for healthcare (CSA)

The call opens on 10th February 2027 

HORIZON-HLTH-2027-01-STAYHLTH-01: Addressing disabilities through the life course to support independent living and inclusion (RIA)The call opens on 10th February 2026 

The call opens on 10th February 2027 

HORIZON-HLTH-2027-01-IND-01: Development of cell-free protein synthesis platforms for discovery and/or production of biologicals (RIA)

HORIZON-HLTH-2027-02-IND-02-two-stage: Portable and versatile Point-of-care diagnostics (IA)

The call opens on 10th February 2027 

HORIZON-MISS-2026-02-CANCER-01: Virtual Human Twin (VHT) Models for Cancer Research (RIA)

HORIZON-MISS-2026-02-CANCER-02: Microbiome for early cancer prediction before the onset of disease (RIA)

HORIZON-MISS-2026-02-CANCER-03: Pragmatic clinical trials to optimise immunotherapeutic interventions for patients with refractory cancers (RIA)

HORIZON-MISS-2026-02-CANCER-04: Earlier and more precise palliative care (RIA)

HORIZON-MISS-2026-02-CANCER-05: Boosting mental health of young cancer survivors through the European Cancer Patient Digital Centre  (ECPDC) (IA)

HORIZON-MISS-2026-02-CANCER-06: Development of a research capacity building programme on cancer with and for Ukraine (CSA)

HORIZON-MISS-2026-02-CANCER-07: Improve the Quality of Life of older cancer patients (RIA)

The call opens on 10th February 2026

EDCTP3 CSA call 2026:

• Training and innovation networks for sustained capacity building related to ethics, regulatory and pharmacovigilance, and related digital regulatory platforms.
• Enhancing integrated research and healthcare in sub-Saharan Africa through digital innovation and artificial intelligence. 

IHI call 12 will be an one-stage call for proposals with the following topics:

• HORIZON-JU-IHI-2026-12-01: Boosting innovation for a better understanding of    the determinants of health
• HORIZON-JU-IHI-2026-12-02: Boosting innovation through better integration of fragmented health R&I efforts
• HORIZON-JU-IHI-2026-12-03: Boosting innovation for peopled centred integrated healthcare solutions
• HORIZON-JU-IHI-2026-12-04: Boosting innovation through exploitation of digitalisation and data exchange in healthcare
• HORIZON-JU-IHI-2026-12-05: Boosting innovation for better assessment of the added value of innovative integrated healthcare solutions

HORIZON-HLTH-2026-01-ENVHLTH-01: Towards a better understanding and anticipation of the impacts of climate change on health (RIA)

HORIZON-HLTH-2026-01-ENVHLTH-04: Towards climate resilient, prepared and carbon neutral populations and healthcare systems (RIA)

HORIZON-HLTH-2026-01-ENVHLTH-05: Support for a multilateral initiative on climate change and health research (CSA)

The call opens on 10th February 2026. 

HORIZON-HLTH-2026-01-STAYHLTH-02: Behavioural interventions as primary prevention for Non-Communicable Diseases (NCDs) among young people (RIA)

HORIZON-HLTH-2026-01-STAYHLTH-03: Building public trust and outreach in the life sciences (CSA)

The call opens on 10th February 2026. 

HORIZON-HLTH-2026-01-IND-03: Regulatory science to support translational development of patient-centred health technologies (RIA)

The call opens on 10th February 2026

HORIZON-HLTH-2026-01-CARE-01: Public procurement of innovative solutions for improving citizens' access to healthcare through integrated or personalised approaches (PPI)

HORIZON-HLTH-2026-01-CARE-03: Identifying and addressing low-value care in health and care systems (RIA)

HORIZON-HLTH-2026-04-CARE-04: Enhancing and enlarging the European Partnership on Personalised Medicine (EP PerMEd) (Top-up) (Programme Cofund Actions)

The call opens on 10th February 2026

HORIZON-HLTH-2026-01-DISEASE-02: Innovative interventions to prevent the harmful effects of using digital technologies on the mental health of children and young adults (RIA)

HORIZON-HLTH-2026-01-DISEASE-03: Advancing research on the prevention, diagnosis, and management of post-infection long-term conditions (RIA)

HORIZON-HLTH-2026-01-DISEASE-04: Development of novel vaccines for viral pathogens with epidemic potential (RIA)

HORIZON-HLTH-2026-01-DISEASE-09: Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD) (RIA)

HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways (RIA)

HORIZON-HLTH-2026-02-DISEASE-12: European Partnership on Rare Diseases (ERDERA) (Phase 2) (Programme Cofund Actions)

HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health (CSA)

The call opens on 10th February 2026. 

HORIZON-HLTH-2026-01-TOOL-03: Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing (RIA)

HORIZON-HLTH-2026-01-TOOL-05: Pilot actions for follow-on funding: Leveraging EU-funded collaborative research in regenerative medicine (IA)

HORIZON-HLTH-2026-01-TOOL-06: Support to European Research Area (ERA) action on accelerating New Approach Methodologies (NAMs) to advance biomedical research and testing of medicinal products and medical devices (CSA)

HORIZON-HLTH-2026-01-TOOL-07: Establishing a European network of Centres of Excellence (CoEs) for Advanced Therapies Medicinal Products (ATMPs) (CSA)

The call opens on 10th February 2026

In 2026, the European Partnership for Brain Health will launch two Calls for Proposals for Multinational Translational Research Projects:

• Call 1: Biological, social and environmental factors that impact the trajectory of brain health across the lifespan – in the field of neurological, mental and sensory disorders
• Call 2: Biological, social and environmental factors that impact the trajectory of brain health across the lifespan – in the field of neurodegenerative disorders

EDCTP3 RIA call 2026 (pre-proposals):

• Global collaboration action for the development of TB drugs for therapy and chemoprophylaxis in adults and children in sub-Saharan Africa.
• Global collaboration action for prevention and treatment of lower respiratory tract infections (LRTIs) in sub-Saharan Africa.
• Global collaboration action towards better prevention, treatment and clinical management of HIV co-infections or co-morbidities in sub-Saharan Africa.
• Global collaboration action on climate and health in sub-Saharan Africa. 

DIGITAL-2026-AI-09-SOLUTIONS-CANCER-STEP

By building on, extending and leveraging the Cancer Image Europe platform, this action is expected to facilitate the uptake of EU AI-driven solutions in medical imaging (including Machine Learning and Generative AI), towards their deployment in clinical settings. It should also include upskilling of healthcare professionals and evidence generation to evaluate the performance of the deployed AI-driven solutions and engage patients.

The Twinning Call 2026 is designed to accelerate the implementation of personalised medicine (PM) solutions or approaches from one country to another through peer-to-peer exchanges.

This is an 1-stage call. 

The goal of this call is to solve Undiagnosed Rare Genetic diseases and to address complex, multifactorial Rare Non-Genetic diseases by identifying causative variants in patients with no molecular diagnosis after prior genetic or genomic testing and providing diagnostic clarity for conditions of unknown or mixed pathogenesis.

12. February 2026 is deadloine for submission of pre-proposals

With this JTC, EP PerMed will fund research projects in human health on innovative PM strategies for patients with cardiovascular, metabolic or kidney diseases. Research projects may focus on a single disease or explore these conditions in combination. 

This is a 2-stage call. The 10th February 2026 is deadline for 1st stage proposals.

The aim of this first EUP OHAMR Call is to improve the treatment success rates of the patients, animals and plants affected by bacterial or fungal infections by providing new treatment options while reducing the risk of resistance in the different One Health settings.

Topic 1: Identify and develop new combination treatments using existing or innovative antimicrobials or antimicrobial with adjunctive treatments to extend drug efficacy and combat resistance.

Topic 2: Develop tools and methods to improve adherence to treatment protocols.

Topic 3: Assess the impact of antimicrobials for veterinary and agricultural use on the risk of AMR transmission to humans and the environment to inform policies on the restriction of some antimicrobials for human use.

The call is aiming to fund research and innovation projects that contribute to ensuring equitable access to and utilisation of health and care services and provide policy and decision makers with the knowledge and tools needed to implement resource reallocation as the health and care system transitions to address new and ongoing challenges.

2nd February is the deadline for submission of pre-proposals

The aims of the call are:
- to support randomised interventional multi-country Investigator-Initiated Clinical Studies that are designed as pragmatic comparative-effectiveness studies and/or drug repurposing studies.
- to encourage and enable transnational collaboration between clinical/public health research teams (from hospital/ public health, healthcare settings and other healthcare organisations) that conduct multi-country IICS, either comparative-effectiveness or drug repurposing studies.

The call opens on November 6th 2025

The call will finance research that improves the understanding of the causes for obesity, overweight and its complications by using a mechanistic approach, as well as studies aiming at the development of public health strategies for the prevention of obesity and overweight by focusing on critical transitional periods of life, which are due to either biological or socio-environmental changes.

The call opens on November 13th 2025

EP PerMed will fund innovation projects in human health that focus on multimodal data usage for PM approaches providing more efficient and personalised management of multimorbid patients, having at least two chronic diseases that require management.

This is a 2-stage call. The 12th January 2026 is deadline for 1st stage proposals.

• EU4H-2026-SANTE-PJ-01 - Call for proposals to pilot and implement cancer screening programmes for gastric cancer (CR/CV&NCD -g-25-12)
• EU4H-2026-SANTE-PJ-02 - Call for proposals to pilot and implement cancer screening programmes for lung cancer (CR/CV&NCD -g-25-13)
• EU4H-2026-SANTE-PJ-03 - Call for proposals to pilot and implement cancer screening programmes for prostate cancer (CR/CV&NCD-g-25-14)
• EU4H-2026-SANTE-PJ-04 - A European flagship initiative leveraging AI and health data for cardiovascular health and related non-communicable diseases: Advancing Risk Prediction, Prevention, Treatments, Personalised Care and Rehabilitation (CR/CV&NCD-g-25-16)
• EU4H-2026-SANTE-PJ-05 - Call for proposals on lifelong prevention for a healthy life with focus on cardiovascular diseases (CR/CV&NCD-g-25-18)
• EU4H-2026-SANTE-PJ-06 - Call for proposals to support the development of a medicine pricing, reimbursement and access tracker through the EURIPID database (HS-g-25-20)
• EU4H-2026-SANTE-PJ-07 - Call for proposals for a programme on orphan medical devices, in particular targeting paediatric patients (HS-g-25-24)
• EU4H-2026-SANTE-PJ-08 - Call for proposals for health data for biotech innovation leveraging the European Health Data Space (DI-g-25-31)
• EU4H-2026-SANTE-PJ-09 - Call for proposals to contribute to the organisation of conferences (OA-g-25-33) 

The STEP funding is offering a continuously updated state-of-play of funding opportunities supported by the EU budget and dedicated to projects related to strategic technologies contributing to STEP objectives. 

• Call for proposals to support the development of innovative medical countermeasures for chemical, biological, radiological and nuclear threats (HERA) - Reusable respiratory personal protective equipment (PPE; EU4H-2025-HERA-PJ-1-b)
• Call for proposals for the development of new diagnostic tests for vector-borne diseases (EU4H-2025-HERA-PJ-2)
• Call for proposals to support the development of innovative medical countermeasures for chemical, biological, radiological and nuclear threats (HERA) - Medicinal products (EU4H-2025-HERA-PJ-1-a)
• Call for proposals to support the development of innovative medical countermeasures for chemical, biological, radiological and nuclear threats (HERA) - Medicinal products (EU4H-2025-HERA-PJ-1-a)

TOPIC 1: Hands-on training on the detection and characterisation of micro(nano)plastics in media contributing to human exposure (such as food, drinking water, soil).

TOPIC 2: Hands-on training on the detection and characterisation of (innovative) nanomaterials in food, as well as investigation of contaminants arising from food processing of novel ingredients.

TOPIC 3: Hands-on training on the synthesis and advanced characterisation of nanomedicines including liposomal drug products, Lipid Nanoparticles-mRNA.

TOPIC 4: Hands-on training on 3D bioprinting and imaging techniques.

• HORIZON-NEB-2025-01-REGEN-01: Applying regenerative design to the built environment in neighbourhoods

EIC Pathfinder Call: Generative-AI based Agents to Revolutionize Medical Diagnosis and Treatment of Cancer

Remark: there are many other interesting topics in the EIC 2025 Work Programme