IHI call 12 will be an one-stage call for proposals with the following topics:

HORIZON-JU-IHI-2026-12-01: Boosting innovation for a better understanding of    the determinants of health

HORIZON-JU-IHI-2026-12-02: Boosting innovation through better integration of fragmented health R&I efforts

HORIZON-JU-IHI-2026-12-03: Boosting innovation for peopled centred integrated healthcare solutions

HORIZON-JU-IHI-2026-12-04: Boosting innovation through exploitation of digitalisation and data exchange in healthcare

HORIZON-JU-IHI-2026-12-05: Boosting innovation for better assessment of the added value of innovative integrated healthcare solutions

In 2026, the European Partnership for Brain Health will launch two Calls for Proposals for Multinational Translational Research Projects:

• Call 1: Biological, social and environmental factors that impact the trajectory of brain health across the lifespan – in the field of neurological, mental and sensory disorders
• Call 2: Biological, social and environmental factors that impact the trajectory of brain health across the lifespan – in the field of neurodegenerative disorders

The Twinning Call 2026 is designed to accelerate the implementation of personalised medicine (PM) solutions or approaches from one country to another through peer-to-peer exchanges.

This is an 1-stage call. 

The goal of this call is to solve Undiagnosed Rare Genetic diseases and to address complex, multifactorial Rare Non-Genetic diseases by identifying causative variants in patients with no molecular diagnosis after prior genetic or genomic testing and providing diagnostic clarity for conditions of unknown or mixed pathogenesis.

12. February 2026 is deadloine for submission of pre-proposals

With this JTC, EP PerMed will fund research projects in human health on innovative PM strategies for patients with cardiovascular, metabolic or kidney diseases. Research projects may focus on a single disease or explore these conditions in combination. 

This is a 2-stage call. The 10th February 2026 is deadline for 1st stage proposals.

The aim of this first EUP OHAMR Call is to improve the treatment success rates of the patients, animals and plants affected by bacterial or fungal infections by providing new treatment options while reducing the risk of resistance in the different One Health settings.

Topic 1: Identify and develop new combination treatments using existing or innovative antimicrobials or antimicrobial with adjunctive treatments to extend drug efficacy and combat resistance.

Topic 2: Develop tools and methods to improve adherence to treatment protocols.

Topic 3: Assess the impact of antimicrobials for veterinary and agricultural use on the risk of AMR transmission to humans and the environment to inform policies on the restriction of some antimicrobials for human use.

The call is aiming to fund research and innovation projects that contribute to ensuring equitable access to and utilisation of health and care services and provide policy and decision makers with the knowledge and tools needed to implement resource reallocation as the health and care system transitions to address new and ongoing challenges.

2nd February is the deadline for submission of pre-proposals

Pre-announcement

The aims of the call are:
- to support randomised interventional multi-country Investigator-Initiated Clinical Studies that are designed as pragmatic comparative-effectiveness studies and/or drug repurposing studies.
- to encourage and enable transnational collaboration between clinical/public health research teams (from hospital/ public health, healthcare settings and other healthcare organisations) that conduct multi-country IICS, either comparative-effectiveness or drug repurposing studies.

The call opens on November 6th 2025

Pre-announcement

The call will finance research that improves the understanding of the causes for obesity, overweight and its complications by using a mechanistic approach, as well as studies aiming at the development of public health strategies for the prevention of obesity and overweight by focusing on critical transitional periods of life, which are due to either biological or socio-environmental changes.

The call opens on November 13th 2025

EP PerMed will fund innovation projects in human health that focus on multimodal data usage for PM approaches providing more efficient and personalised management of multimorbid patients, having at least two chronic diseases that require management.

This is a 2-stage call. The 12th January 2026 is deadline for 1st stage proposals.

• EU4H-2026-SANTE-PJ-01 - Call for proposals to pilot and implement cancer screening programmes for gastric cancer (CR/CV&NCD -g-25-12)
• EU4H-2026-SANTE-PJ-02 - Call for proposals to pilot and implement cancer screening programmes for lung cancer (CR/CV&NCD -g-25-13)
• EU4H-2026-SANTE-PJ-03 - Call for proposals to pilot and implement cancer screening programmes for prostate cancer (CR/CV&NCD-g-25-14)
• EU4H-2026-SANTE-PJ-04 - A European flagship initiative leveraging AI and health data for cardiovascular health and related non-communicable diseases: Advancing Risk Prediction, Prevention, Treatments, Personalised Care and Rehabilitation (CR/CV&NCD-g-25-16)
• EU4H-2026-SANTE-PJ-05 - Call for proposals on lifelong prevention for a healthy life with focus on cardiovascular diseases (CR/CV&NCD-g-25-18)
• EU4H-2026-SANTE-PJ-06 - Call for proposals to support the development of a medicine pricing, reimbursement and access tracker through the EURIPID database (HS-g-25-20)
• EU4H-2026-SANTE-PJ-07 - Call for proposals for a programme on orphan medical devices, in particular targeting paediatric patients (HS-g-25-24)
• EU4H-2026-SANTE-PJ-08 - Call for proposals for health data for biotech innovation leveraging the European Health Data Space (DI-g-25-31)
• EU4H-2026-SANTE-PJ-09 - Call for proposals to contribute to the organisation of conferences (OA-g-25-33) 

The STEP funding is offering a continuously updated state-of-play of funding opportunities supported by the EU budget and dedicated to projects related to strategic technologies contributing to STEP objectives. 

• Call for proposals to support the development of innovative medical countermeasures for chemical, biological, radiological and nuclear threats (HERA) - Reusable respiratory personal protective equipment (PPE; EU4H-2025-HERA-PJ-1-b)
• Call for proposals for the development of new diagnostic tests for vector-borne diseases (EU4H-2025-HERA-PJ-2)
• Call for proposals to support the development of innovative medical countermeasures for chemical, biological, radiological and nuclear threats (HERA) - Medicinal products (EU4H-2025-HERA-PJ-1-a)
• Call for proposals to support the development of innovative medical countermeasures for chemical, biological, radiological and nuclear threats (HERA) - Medicinal products (EU4H-2025-HERA-PJ-1-a)

TOPIC 1: Hands-on training on the detection and characterisation of micro(nano)plastics in media contributing to human exposure (such as food, drinking water, soil).

TOPIC 2: Hands-on training on the detection and characterisation of (innovative) nanomaterials in food, as well as investigation of contaminants arising from food processing of novel ingredients.

TOPIC 3: Hands-on training on the synthesis and advanced characterisation of nanomedicines including liposomal drug products, Lipid Nanoparticles-mRNA.

TOPIC 4: Hands-on training on 3D bioprinting and imaging techniques.

• HORIZON-NEB-2025-01-REGEN-01: Applying regenerative design to the built environment in neighbourhoods

EIC Pathfinder Call: Generative-AI based Agents to Revolutionize Medical Diagnosis and Treatment of Cancer

Remark: there are many other interesting topics in the EIC 2025 Work Programme